Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in all living cells, playing a pivotal role in energy production, DNA repair, and overall cellular health. As we age, NAD+ levels naturally decline, which has spurred interest in supplementation to counteract age-related cellular deterioration.

Benefits and Scientific Research

Elevating NAD+ levels has been associated with several potential health benefits:

• Energy Metabolism: NAD+ is essential for converting nutrients into cellular energy (ATP), thereby supporting metabolic processes.

• DNA Repair: It activates enzymes involved in DNA repair mechanisms, maintaining genomic stability.

• Neuroprotection: Some studies suggest that increased NAD+ may protect against neurodegenerative diseases by enhancing neuronal survival.

While animal studies have shown promising results, human research is still emerging. Some experts caution against viewing NAD+ as a panacea, emphasizing the need for more robust clinical trials to substantiate these claims. (source: ft.com)

Administration Methods: Injections vs. Capsules

NAD+ can be supplemented through various methods, primarily injections and oral capsules, each with distinct characteristics:

• Injections: Delivering NAD+ directly into the bloodstream via intravenous (IV) or intramuscular (IM) injections ensures immediate availability and higher bioavailability, as it bypasses the digestive system. This method is often utilized in clinical settings for rapid effects, such as boosting energy and cognitive function. However, typically it requires medical supervision, can be costly, and carries potential risks like infection at the injection site.

• Oral Capsules: These typically contain NAD+ precursors like nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), which the body converts into NAD+. While more convenient and cost-effective, oral supplements may have lower bioavailability due to digestive breakdown, resulting in a slower onset of effects. Consistent, long-term use is generally necessary to achieve desired outcomes.

In conclusion, while NAD+ supplementation holds promise for enhancing cellular health and mitigating some effects of aging, individuals should carefully consider the method of administration and choose reputable products backed by scientific evidence and quality assurance.

We will be producing further articles & videos talking about NAD+ further, comparing the products available in the marketplace and giving you our opinion. Please let us know any questions you may have on this topic, including your own experience of using NAD+.